Paradol Cold & Flu

Paradol Cold & Flu
22 Nov

Paradol Cold & Flu

Analgesics, Antipyretics, Anti-Inflammatory drugs
  • Paracetamol is a para-aminophenol derivative, it is a non-opioid, nonsalicylate. It Has an analgesic, antipyretic properties and weak anti-inflammatory activity.
  • Pseudoephedrine Hcl is a sympathomimtic agent, for sympathomimtic relief from nasal congestion.
  • Chlorpheniramine maleate is an alkylamin derivative, it is a sedating antihistamine that causes a moderate degree of sedation it also has antimuscarinic activity.
  • Paracetamol and Pseudoephedrine are readily absorbed from the gastrointestinal tract. However, Chlorpheniramine maleate is absorbed relatively slowly from the gastro-intestinal tract.
  • The triple components are widely distributed in the body, including placenta and breast milk.
  • Unchanged drug and metabolites for the three compounds are excreted in the urine.

Ingredients

  • 500mg
  • 30mg
  • 2mg

Indecation

Paradol® Cold & Flu is indicated for the relieve of symptoms of
common cold and flu such as :Fever, nasal congestive, sinus congestion, headache and sinus pain, sneezing, itchy and watery eyes.

Dosage & Administration

  • Paradol® Cold & Flu caplets are suitable for adults and children over 12 wyears of age.
  • Paradol® Cold & Flu caplets are used in doses of 2 caplets every 6 hours-8 hours. And it is possible to repeat the dose if necessary. Do not exceed 8caplets in 24 hours.
  • * Do not give to children below 12 years of age.
  • Each film coated caplet of Paradol® Cold & Flu contains:
    • Paracetamol 500 mg
    • Pseudoephedrine Hcl 30 mg
    • Chlorpheniramine maleate 2 mg
  • Paradol® Cold & Flu caplets is contra-indicated in the following cases:
    • Hypersensitivity to any of the ingredients.
    • Should not be used by patients taking monoamine oxidase inhibitors, antidepressants or within two weeks of stopping such treatment.
    • Hepatic or renal dysfunction.
  • Paracetamol: Paradol® Cold & Flu caplets may interact with anticoagulant agents on prothrombin time.
  • The liver effects of Paradol® Cold & Flu caplets may be increased by the use of alcohol and the concomitant use of certain drugs which enhance the metabolism of Paracetamol in the liver (i.e. barbiturates, tricyclic antidepressants).
  • Coadministration of pseudoephedrine and MAOI,s may lead to hypertensive crisis.This effect may persist for up to 2weeks after discontinuation of MAOI,s.
  • Enhanced sedative effects of Chlorpheniramine can occur with simultaneous administration of alcohol, anxiolytics and hypnotics. Tricyclic antidepressants and antimuscarinics can increase antimuscarinic side effects.
  • As with any drug medical advice should be taken before using Paradol® Cold& Flu
  • Paradol® Cold & Flu should not be used during breast feeding as there may be risks associated with use of antihistamines in infants.
  • Paracetamol when taken in recommended doses, is usually free from side effects. However, skin reactions such as urticaria have been reported rarely.
  • Pseudoephedrine Hcl may occasionally cause anxiety, tremor,dizziness, or cardiovascular effects including tachycardia , hypertension, insomnia and urinary retention.
  • Chloropheniramine the antihistamine, may cause sedation, gastrointestinal disturbances, and antimuscarinic effects.
  • Paradol® Cold & Flu caplet should be administered with caution in patients with:
    • Sever hypertension, cardiac or peripheral vascular disease .
    • Hyperthyrodism, diabetes mellitus or epilepsy.
    • Breathing problem such as emphysema or chronic bronchitis, glaucoma or difficulty in urination due to enlargement of the prostate gland.
  • Do not take this product over 10 days or for fever more than 3 days unless directed by a doctor.
  • Do not take other medication contining Paracetamol, nasal decongestants or anti histamines at the same times, with Paradol® Cold & Flu.
  • Caution is also indicated when driving or operating machinery because the drug contain an antihistamine with sedation effects .
  • Blister of 10 caplets, Pack of 2 blisters.
  • Blister of 10 caplets, Pack of 10 blisters.
  • Hospital of different sizes.
  • Store in a dry place at tem prature below 30°C.