Zimasafe 100mg 30ml
- Cefixime is a broad spectrum semi-synthetic third generation
cephalosporin antibiotic for oral administration.
-The bactericidal action of Cefixime results from inhibition of cell wall
synthesis. Cefixime is highly beta- lactamase stable, so many bacteria that
resist penicillins and other cephalosporins are susceptible to Cefixime .
- About 40 -50 %of Cefixime is absorbed, peak serum concentrations occur
between 2- 6 hours after oral administration, approximately 50% of
absorbed dose is excreted unchanged in urine within 24 hours.
- Cefixime has been shown to be active against most strains of the
following Gram-positive and Gram-negative organisms:
Streptococcus pneumonia, Streptococcus pyogenes, Streptococcus
agalctiae, Haemophilus influenze, Haemophilus parainfluenzae, Moraxella
(Branhamella) catarrhalis, Escherichia coli, Proteus mirabilis, Proteus
vulgaris, Neisseria gonorrhoeae, Klebsiella pneumoniae, Klebsiella
oxytoca, Pasteurella multocida, Providencia species, Salmonella species,
Shigella species, Citrobacter diversus, Serratia marcescens.