Clobisol Ointment
-Clobisol® is a corticosteroid used topically for its glucocorticoid activity in the treatment of various skin disorders.
7
Jun
Indecation
-Clobisol® is of particular value when used in short courses for the treatment of:
- Psoriasis ( excluding widespread plaque
Psoriasis).
- Recalcitrant eczemas.
- Lichen Planus.
- Discoid lupus erythematosus.
- And other conditions which do not respond
satisfactorily to less active steroids.
Dosage & Administration
-Apply a thin film of Clobisol® sparingly to the affected area once or twice daily until improvement occurs and therapy should be discontinued when control is achieved.
-If no improvement is seen within two to four weeks, reassessment of the diagnosis, or referral may be necessary.
-If continues steroid treatment is necessary, less potent preparations should be used.
-In very resistant lesions, especially where there is hyperkeratosis, the anti-inflammatory effect of Clobisol® can be enhanced, if necessary by overnight occluding the treatment area with polythene film, and thereafter the improvement can be maintained by application without occlusion.
-Clobisol®cream/ointment contains:
Clobetasol propionate 0.05% w/w
-Clobisol® is contraindicated in:
-Patients with hypersensitivity to Clobetasol propionate.
-Treatment of simple skin diseases, especially in face and genitals.
-Rosacea ,acne vulgaris, peri oral dermatitis, primary cutaneous viral infections as Herpes simplex and chickenpox.
-The treatment of primarily infected skin lesions caused by infection with fungi(e.g : Candidiasis, Tinea ), or bacteria (e.g : Impetigo) and perianal and genital Pruritus.
-Clobisol® is not used to treat Dermatoses in children under one year of age, including dermatitis and napkin eruptions.
-Clobetasol propionate is well tolerated, but if signs of hypersensitivity occur, application should be stopped immediately.
-As with other topical corticosteroids, prolonged use of large amounts or treatment of extensive areas can result in sufficient systemic absorption to produce the features of hypercorticism.
-Prolonged and intensive use of Clobetasol propionate may cause atrophic changes, such as :
Striae, thinning of the skin, and dilatation of the superficial blood vessels particularly when occlusive dressings are used or where skin folds are involved.
-Long term continuous topical therapy of Clobisol®should be avoided where possible, particularly in infants and children, as adrenal suppression can occur.
-If possible, do not use Clobisol® for more than five days on the face and avoid occlusion.
-Appropriate antimicrobial therapy should be used whenever treating inflammatory lesions which have become infected.
-No approved findings for abnormalities to human fetus, however Clobisol® should not be used extensively in pregnancy.
Store at a temperature not exceeding 25°C.
-Clobisol® cream: tube of 20gm.
-Clobisol® ointment: tube of 20gm.