Depavalin 250
- The active substance in Depavalin® Solution is sodium
valproate which has anticonvulsant effect properties including
various types of human epilpesy.
Indecation
- Depavalin® Solution is used for treatment of various types
of seizures of epilepsy.
- It is also used in children to prevent fever related seizures.
Dosage & Administration
Depavalin® Solution treatment must be started and
supervised by a doctor specialised in the treatment of
epilepsy, so you should take drug exactly as your doctor has
told you.
- The primary dose of Depavalin® depend on body weight
and seriousity of case and patient experience to medicine,
which indicated in the following table:
العمر الوزن بالكيلوجرام الجرعة اليومية (مجم) الجرعة اليومية (مل)
من 3 إلى 6 أشهر 5.5 -7.5 كجم 150 مجم 3 مل
من 6 إلى 12 شهر 7.5 – 10 كجم 150 – 300 مجم 3 -6 مل
من سنة إلى 3 سنوات 10 – 15 كجم 300 -450 مجم 6 – 9 مل
من 3 إلى 6 سنوات 15 – 20 كجم 450 – 600 مجم 9 – 12 مل
من 7 إلى 11 سنة 20 – 40 كجم 600 1200 مجم 12 – 24
- Each 5 ml of Depavalin® Solution contains:
Sodium valproate 250 mg
Depavalin® Solution is contrainticated in:-
- Hypersensitivity to sodium valproate.
- Disturbed function of the liver or pancrease.
- Taking mefloquine & lamotrigine and St. John Wort plant
- Salicylates should not be given with Depavalin® Solution.
- The dosage of antidepressants, anticonvulsants and
anticoagulants should be reduced when administration
concomitantly with Depavalin® Solution.
- you must tell your doctor if you are taking any other
medicines.
- You must not use Depavalin® during pregnancy or lactation
unless it is advised to do so by the physician.
- If you are of childbearing age, you must use a relieble means
of contraception during treatment
- Like all medicines, Depavalin® Solution can cause side
effects, although not everybody gets them.
- Nausea, vomiting, stomach pain, diarrhea (at the start of
treatment), temporary hair loss, slight shaking of the hands,
drawsiness: these effects are temporary but may nonetheless
require adjustment of the dosage by your doctor.
- Menstrual disturbances, weight gain.
- Consciousness disturbances that may be isolated or
associated with an increase in epileptic seizures.
- Abnormal laboratory values: reduction in the number of
platelets (sometimes manifested by slight bleeding of the
nose, gums), in white blood cells (sometimes manifested by
fever), in red blood cells (sometimes manifested by
breathlessness, unusual pallor) or fibrinogen. Prolonged
bleeding time, change in the size of red blood cells and
increased blood ammonia levels.
You must inform your doctor quickly of any abnormal
laboratory value.
- Decreased blood sodium levels (sometimes manifesteby
confusion).
- Allergic reactions along with fever, impaired general health,
skin rash, liver or kidney damage, excessive amount of
certain types of while blood cells (eosinophils). You must
immediately inform your doctor if any of these symptoms
occur.
- If your condition is not controlled, i.e. if you continue to have
seizures or drowsiness it is dangerous to drive or operate
potentially dangerous machines.
- Depavalin® Should be carefully used in children under
3 years of age especially those with congenital metabolic
disorders or mental retardation.
- Liver, pancrease and kidney functions as well as blood
Coagulation must be checked regularly during treatment.
- Small number of people being treated with antiepileptics have
had thoughts of harming or killing themselves, if this happens
contact your doctor immediately.
Depavalin® Solution: Bottle of 100 ml solution.
Store at a temperature below 25 °C, protected from light.