Common vitamin reprograms immunity to fight cancer

A recent study were published in "SCIENCE TRANSLATIONAL MEDICINE" journal, indicated that Niacin "vitamin B3" may help reprogram immune cells in the brain and help them fight glutinoblastoma.
This type of tumor is the most lethal of the brain tumors and resistant to various treatments, and the average period of survival of those affected by it does not exceed fifteen months.
Treatment for glioblastoma is difficult because the brain's immune cells - including monocytes and macrophages - fail to attack it. Rather, the tumor reprogramms immune cells and uses them to promote tumor growth and achieve lethal spread.
Building on the prior work to identify drug compounds that can reprogram immune cells in the brain to fight tumors, researchers have made promising progress in discovering the ability of niacin to enhance the ability of immune cells to attack glial tumors.
Niacin is a common vitamin that the body makes and uses to convert food into energy. It also helps maintain the health of the nervous and digestive systems, skin and hair.
Researchers say that giving calculated doses of niacin to experimental rats suffering from gliomas that are highly resistant to chemotherapy helped them prevent the tumor from developing and prolonging its life.
The combination of niacin with approved chemical treatments has reactivated immune cells in mice, stimulating them to attack tumor cells, and enhancing their resistance to glial cancer.

* Source: Scientific American