Nistan

Nistan
17 May

Nistan

Anti-Fungal

Nistan® is a polyene antifungal antibiotic which interferes with the permeability of the cell membrane of sensitive fungi.                                   
-    It has main action against Candida spp. 
-    Nistan® especially formulated for the treatment of oral, intestinal, vulvovaginal and cutaneous mycotic infections caused by candida albicans.
-     Nistan® is poorly absorbed from the gastrointestinal tract. 
-     Nistan® oral suspension is artificially sweeted, so it is suitable for diabetic patients.

Indecation

    Nistan® is used for the prophylaxis and treatment of candidiasis of the skin and mucous membranes that include oropharynx, and oesophagous. 
-    For the treatment of intestinal candidiasis.
-    For prophylaxis of intestinal candidiasis in patients receiving broad-spectrum antibacterials.

Dosage & Administration

-By mouth by using standard dropper:
Adults:
  5 ml every 6 hours.

Infants and children:
 1 ml or more may be given 4 times daily.
-    For the treatment of candidiasis of oral cavity:
  1 ml 4 times daily.The preparation should be kept in the mouth as long as possible before swallowing, 
  and patients should avoid taking food or drink for 
  one hour after taking the dose.

    Continue the treatment for at least 48 hours after perioral symptoms have disappeared to prevent relapse.
-    For prophylaxis of intestinal candidiasis in patients receiving broad-spectrum antibacterials, 
  10 ml daily may be given.

-Each 1 ml of Nistan® Oral Suspension Drops contains: NYSTATIN 100000 I.U .

Hypersensitivity to nystatin.

With oral treatment, in order to achieve maximum effect from  Nistan® ,any propulsive or digestive agent and generally any  agent capable to isolate the mucous membrane from the activity of the drug has to be avoided.


-    Nausea,vomiting and diarrhoea have occasionally been reported after oral use of nystatin.
-    Oral irritation or sensitisation may occur.

n pregnant women,  Nistan® must be administered only in case of real necessity and only under direct control of physician. 
-    It is not know whether nystatin is excreted in human milk, caution should be taken when  Nistan® is prescribed to a nursing women.
-    Unlicensed for treatment of candidiasis in neonate.

-Bottle of 30 ml oral suspension drops with 
  standard dropper.

-Store at temperature below 30° C, protected
   from direct light.