Paradol Extra

Paradol Extra
21 Nov

Paradol Extra

Analgesics, Antipyretics, Anti-Inflammatory drugs
  • Paracetamol is a para-aminophenol derivative, it is a non-Opioid non salicylate. It has analgesic, antipyretic properties and weak anti-inflammatory Activity.
  • Paracetamol produces central and peripheral analgesia by elevation of the pain threshold and inhibition of prostaglandin biosynthesis, and antipyretic action through the effect on the hypothalamic  heat-regulating center, resulting in peripheral vasodilatation, increased blood flow through the skin, sweating and heat loss.
  • Paracetamol is readily absorbed from the gastro-intestinal tract with beak plasma concentertion occurring about 10 to 60 minutes after oral administration.
  • Paracetamol is distributed into most body tissues. It crosses the placenta and is present in breast milk .
  • Paracetamol is metabolised predominantly in the liver and excreted in the urine mainly as the glucuronide and sulphate conjugates. Less than 5% is excreted as unchanged Paracetamol .
  • The elemination half-life of Paracetamol varies form about 1to3hours.
  • Caffeine is absorbed readily after oral does and is widely distributed in the body. It is also absorbed through the skin.
  • Caffeine passes realily in to the CNS. Low concentrations are also present in breast milk.
  • Caffeine is metabolised almost Completely in the liver and exereted in urine.
  • The elimination half- life of Caffeine are about 3 to 7 hours.

Ingredients

  • 500mg
  • 65mg

Indecation

  • Paradol® ExtraTablets are indicated for the relief of pain and fever from: headache, migraine, common colds and flu, sore throat, earache, toothache, backache, rheumatic and muscular pain, neuralgia and period pain.

Dosage & Administration

  • Paradol® Extra Tablets are suitable for adults and children over 12 years of age :- two tablets up to four times a day.
  • Not recommended for children under 12 years.
  • If necessary the dose may be repeated every four hours but do not take more than four doses in 24 hours.

Each Tablet of Paradol® Extra Contains:

  • Paracetamol 500 mg.
  • Caffeine 65 mg.
  • Paradol® ExtraTablets are contra-indicated in patients with known hypersensitivity to Paracetamol.
  • Paradol® Extra Tablets may interact with anticoagulant agents on prothrombin time.
  • The liver effects of Paradol® Extra tablets may be increased by the use of alcohol and the concomitant use of certain drugs which enhance the metabolism of Paradol® Extra in the liver (ie.barbiturates, tricyclic antidepressants).
  • Although there is epidemiological evidence of the safety of Paracetamol in pregnancy and lactation, medical advice should be sought before using this product.

When taken in recommended doses, Paradol® Extra is usually free from side-effects.However skin reactions such as urticaria have been reported rarely.

  • This preparation contains Paracetamol. Do not take other Paracetamol containing medications at the same time.
  • Paradol® Extra tablets should be used with caution in cases of severe liver or kidney damage.
  • Do not take this product for pain for more than 10 days or for fever for more than 3 days unless directed by a doctor . If pain or fever persists or gets worse, if new symptoms occur, or if redness
  • and swelling is present, consult a doctor because these could be signs of a serious condition.
  • If sore throat is severe and persists for more than 2 days, is accompanied by fever, headache, rash, nausea or vomiting, consult a doctor promptly.

Blister of 10, 12 tablets, Pack of 2 blisters.
Blister of 10, 12 tablets, Pack of 10 blisters.
Hospital packs with different sizes.

Store below 25Co in a dry place and protect from light.